Photonuclear Production of 67Cu and the Issues Associated
Department of Physics
Idaho State University
radionuclide Cu-67 is considered one of the most promising beta-emitting
radio-isotopes for radioimmunotherapy. The available production methods using
cyclotrons and high-flux nuclear reactors do not meet potential market needs.
This talk will discuss the photonuclear production of Cu-67 through the
reaction 68Zn(γ,p)67Cu. For commercial scale production,
a high activity yield of Cu-67 is needed. Several parameters are
investigated to maximize the photo-production of Cu-67
including: electron beam parameters, design and materials of the end
station (an integrated converter and target as well as cooling system), possible
radiolytic reactions in the high radiation field, and finally, separating Cu-67
from the zinc target material. Computer simulations and experiments performed
at the Idaho Accelerator Center (IAC) on some of the above issues will be discussed.